CD40L-CD40 interaction avidity as coronary artery disease predictive factor

CD40-CD40L: a Janus-faced interaction.

The common denominator of arterial diseases is inflammation. Co-stimulatory molecules are essential to propagate and modulate immune reactions and thus the inflammatory response (1). In diseases such as atherosclerosis and restenosis, the co-stimulatory CD40-CD40L dyad plays a pivotal role. However, both CD40 and CD40L have Janus-faced properties. In the majority of studies, genetic or pharmaco...

ارتباط میان عفونت هلیکوباکترپیلوری با coronary artery disease

چکیده ندارد.

Supportive Data for Galectin-3 as a Prognostic Factor in Coronary Artery Disease

Introduction: Galectin-3 is known as a biomarker in patients with heart failure. This protein participates in different mechanisms involved in atherosclerosis including inflammation and plaque formation. This study was conducted to investigate whether this factor could be a predictive biomarker for the severity of atherosclerosis. Materials and Methods: The study group consisted of 80 patients ...

CD40-CD40L Interaction in Immunity Against Protozoan Infections

Activation of the immune system against protozoan infections relies particularly on two specific signals provided by cognate interaction of T cells with antigen presenting cells (APCs). The first signal is attributed to binding of the T-cell receptor (TCR) to peptide/MHC complexes on the surface of APCs, whereas the second signal is triggered through binding of several costimulatory molecules o...

The Relation between CD40 Ligand and Coronary Artery Disease.